Poly(vinyl alcohol)/ulvan electrospun nanofibers thermallycrosslinked to produce a water stable biomaterial
Luisa Elena Mejía Agüero; Adriana Freire Lubambo; Cyro Ketzer Saul; Beatriz Franco Silva; Rilton Alves de Freitas; Franciely Grose Colodi; Maria Eugênia Rabello Duarte; Miguel Daniel Noseda
Abstract
Ulvan is the main sulfated polysaccharide isolated from green seaweeds of the genus Ulva, showing several biological properties. A fibrous ulvan-based mat exhibiting nanofibers with an average diameter of 144 ± 33 nm, was fabricated from electrospun of an aqueous mixture, composed by poly(vinyl alcohol) (PVA) and ulvan in a 5:2 mass ratio (PVA5U2). As expected from its composition, the PVA5U2 mat readily disintegrated upon contact with water, limiting potential uses. For this reason, mat stabilization against water exposition as well as keeping ulvan functional groups availability in the biomaterial, as fundamental aspects for functionalization purposes, became the main objectives of this work. To achieve them, thermal crosslinking (180 °C/60 min), instead of chemical crosslinking, was used for the first time in this type of biomaterial, modulating the poor stability of the ulvan-based electrospun mat in water and preventing the formation of polysaccharides crosslinking complexes during the stabilization treatment. Infrared spectroscopy and scanning electron microscopy were used to characterize the PVA5U2 mat and the thermally-crosslinked PVA5U2 mat, evidencing the presence of nanofibers and ulvan functional groups. Nanofibers increased 30% in diameter after 180 min of water exposition. The PVA5U2 mat exhibit characteristics that turn them into a versatile biotechnological biomaterial.
Keywords
References
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Submitted date:
07/05/2023
Accepted date:
11/03/2023
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